It is commonly active in the mg range, taken orally, and highly dose-sensitive. Insufflating ie administering the chemical nasally requires a much lower dose, typically not exceeding 5mgs, for noticeable effects, but tends to cause intense pain. Many have reported that the general effects of 2C-E are similar to those of the other psychedelic phenethylamines , but far more intense. Vivid hallucinations similar to those experienced while under the influence of LSD are common, and many reports would indicate that the effects of this particular chemical may be overly intense for those not well experienced with psychedelics [1].
Crystalline forms are obtained as the amine salt by reacting the free base with a mineral acid, typically HCl. Shulgin does not report an exact boiling point for the free base, stating only that during one synthesis the fraction boiling between C at 0. Shulgin also does not report a melting point for the hydrochloride salt.
The melting point of C previously reported in this article is incorrect. The C melt point value refers to the melting point of the hydrochloride salt of 5-ethoxyethylmethoxyphenethylamine 2CE-5ETO in Shulgin's nomenclature. The Material Safety Data Sheet for a commercial sample of 2,5-dimethoxyethylphenethylamine hydrochloride reported the melting point as C. In the absence of a published melting point for a verified sample, the melting point is currently reported in this article as unknown. The total duration of 2C-E's effects is generally between six and ten hours for an average dose, with the plateau lasting between three and six hours.
For such a dose, the onset of effects takes approximately twenty to ninety minutes and perception may be somewhat altered for up to a day after ingestion.
In extreme cases where between seventy-five and one hundred milligrams of 2C-E were ingested, the duration of effects has exceeded twenty-four hours, with plateaus exceeding ten hours in length and an onset of effects within the first five minutes after the ingestion of the drug.
A few users of very high doses have reported "never feeling the same again" after having used this drug. The concurrent use of SSRIs generally has a palliative effect upon both the intensity and duration of the effects of 2C-E during their plateau stage. It's a synthetic hallucinogen called 2C-E , also known as "Europa," and it r eportedly has the same effects as LSD and psychedelic mushrooms. It's available for sale on the Internet, and seems popular among the under raver crowd.
There's been one reported case of an overdose of 2C-E in Phoenix, but other states have seen a larger number of incidents. Ten other people who'd been at the same party, ages 16 through 21, were taken to hospitals after doing the drug. The death has put 2C-E in the current spotlight, but the substance was actually developed more than 30 years ago -- with permission from the United States Drug Enforcement Agency.
The drug was developed by California psychopharmacologist Alexander Shulgin in the s. At the time, Shulgin had a license from the DEA to produce synthetic drugs in his laboratory in order to analyze drugs and provide testimony for prosecutions. In his book, Shulgin describes the effects of 16 mg of 2C-E: "There was a strange devil-angel pairing.
As I was being told of the ecstatic white-light ascent of my partner into the God-space of an out-of-body experience, I was fighting my way out of a brown ooze. Police in Minnesota told media that the victims last week were having difficulty breathing , and some appeared to be hallucinating.
The Arizona Poison and Drug Information Center reports receiving one call related to 2C-E -- in this case, a 19 year-old male was treated in an emergency room in January of this year after reportedly snorting the drug. He was experiencing an increased heart rate, chest pain, agitation, and hallucinations. Like the synthetics in spice and bath salts when they first hit the market, the 2C-E or "Europa" compound is not yet a controlled substance in the U.
Synthetics with similar chemical structures, such as 2C-I and 2C-T-7, are also currently legal stateside. Any drugs with similar chemical structure to 2C-B could be prosecuted under the Federal Analogue Act an analogue is a substance similar to another substance, but usually differs by a single element or variation. Considering how quickly the DEA moved to ban the synthetic compounds in spice, they may move even faster to controll 2C-E -- especially now that it's been pinned to a death in the Midwest.
A number of studies have reported the synthesis of some phenethylamines and amphetamine substitutes. In the s and s, Alexander Shulgin, a biochemist and pharmacologist, reported the synthesis of numerous new psychoactive compounds. Simple variations on the mescaline molecule a natural phenylethylamine led to the synthesis of powerful hallucinogenic substances, e. Over two decades later, a new generation of phenethylamines was researched by Professor David Nichols and his research team at Purdue University in the United States.
The team found the potency of synthetic analogues of mescaline such as 2C-B and DOB, to exceed that of many naturally occurring hallucinogens.
Bromo-Dragonfly is the most common and potent substance in this sub-group.
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